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Rv0682 More about Rv0682 on TBDB.org More about Rv0682 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail Display high confidence mutations only |
| Rv0682: high confidence mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Nair J Mol Micro 1993 | AAG/AGG | 128 | 43 | Lys/Arg | 1950 | USA | Sequencing | Whole gene | S, H, E | N.S | N.S | 40033 | 1/0 | - |  |
| Sreevatsan S AAC 1996 | AAG/CAG | 262 | 88 | Lys/Gln | 1995 | Vietnam | Sequencing | Whole gene | S | >200ug/ml | Proportion method, BACTEC 460 | 78/139 | 1/0 | GTG/ATG, Val/Met | |
| Finken M Mol Micro 1993 | AAG/AGG | 263 | 88 | Lys/Arg | 1993 | - | Sequencing | Whole gene | S | N.S | Proportion method | 38/73 | 2/0 | n/a | |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |