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Rv0682 More about Rv0682 on TBDB.org More about Rv0682 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv0682: Codons 52 to 53: 1 mutation (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Brzostek A IntJ TubLungDis 2004 | GTT/GGT | 155 | 52 | Val/Gly | 2000 | Poland | Sequencing | region of rpsL | S | N.S | Proportion method, BACTEC 460 | 1/88 | 1/0 | Thr52Ser is one of 18 silent mutations and 6 a.a. sub: Lys51Asn, Val41Gly, Gly84Val, Arg86Trp, Val87Leu | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |