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MTB000019 More about MTB000019 on TBDB.org More about MTB000019 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| MTB000019: Nucleotides 850 to 899: 2 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Cooksey RC, AAC 1996 | C/G | 865 | 865 | - | 1994 | USA | Sequencing | 306 bp | RHS | 10 | Agar dilution method | 45/367 | 1/0 | none | - |
| Okamoto S MolMicro 2007 | G/A | 887 | 887 | - | Before 2000 | Japan | Sequencing | - | R, H, S, E, K, PAS | 20 ug/ml | Absolute concentration method | 57/132 | 1/0 | A276C, T563G (gidB) | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |