|
|
           
|
|
|
|
|
|
|
|
 
|
|
MTB000019 More about MTB000019 on TBDB.org More about MTB000019 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| MTB000019: Nucleotides 400 to 449: 2 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Ramaswamy SV J Med Micro 2004 | G/T | 426 | 426 | - | 1996-1998 | Mexico | Sequencing | Whole rrs | RHS | N.S | Proportion method | 39838 | 1/0 | "315, AGC/ACC, Ser/Thr (katG); 450, TCG/TTG, Ser/Leu (rpoB)" | - |
| Spies FS AAC 2008 | G/C | 426 | 426 | - | Published 2008 | Brazil | Sequencing | 530 loop, 912 region | RHSE | >31,5ug/ml | Resazurin microtiter assay | 47/32 | 1/0 | "gidB: CCT/CGT; L16R" | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
|
© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |