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MTB000019 More about MTB000019 on TBDB.org More about MTB000019 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| MTB000019: Nucleotides 1050 to 1099: 1 mutation (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Sekigushi J JCM 2007 | ins C | 1061 | 1061 | Frameshift | 2006 | Japan | Multiplex PCR | 530 loop, 912 region | N.S | N.S | Proportion method, Rapid broth method | 55/138 | 1/0 | Lys121Lys (rpsL), silent mutation, not assoc w/ STR-res. | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |