Rv3795: embBRv0667: rpoB

Rv0667

More about Rv0667 on    TBDB.org

More about Rv0667 on    TubercuList

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Rv0667: Codons 600 to 624: 1 mutation (high confidence mutations are highlighted in yellow)
Primary reference Polymorphism Nucleotide position Codon position Amino acid Time period Origin Molecular detection method Gene coverage Resistance pattern MIC Susceptibility testing method R/Total isolates R/S isolates with mutation Additional mutations High confidence support
Prammananan T CMI 2008 TCG/GCG - 622 Ser/Ala 2003-2005 Thailand Sequencing Whole gene MDR N.S. Proportion method 154/113 1/0 rpoB 531 TCG/TTG ser/Leu -

rpoB disclaimer: All mutation coordinates are in reference to E. coli and not M. tuberculosis.

Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations.


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