Rv3795: embBRv0667: rpoB

Rv0667

More about Rv0667 on    TBDB.org

More about Rv0667 on    TubercuList

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Rv0667: Codons 375 to 399: 1 mutation (high confidence mutations are highlighted in yellow)
Primary reference Polymorphism Nucleotide position Codon position Amino acid Time period Origin Molecular detection method Gene coverage Resistance pattern MIC Susceptibility testing method R/Total isolates R/S isolates with mutation Additional mutations High confidence support
Taniguchi H FEMS Micro 1996 GCG/GTG - 381 Ala/Val Published 1997 Japan Sequencing Whole gene R 200 ug/ml Proportion method, absolute concentration method 21/39 (1/0) - -

rpoB disclaimer: All mutation coordinates are in reference to E. coli and not M. tuberculosis.

Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations.


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