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Rv0667 More about Rv0667 on TBDB.org More about Rv0667 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv0667: Codons 125 to 149: 1 mutation (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Heep M AAC 2000 | GTC/TTC | - | 146 | Val/Phe | Published 2003 | Japan | Sequencing | Whole gene | R | 1-4, 8-32 ug/ml | N.S. | (6/6 || 3 high level of resistance / 6 total) | (3/0) | - | - |
rpoB disclaimer: All mutation coordinates are in reference to E. coli and not M. tuberculosis. |
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Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |