|
|
           
|
|
|
|
|
|
|
|
 
|
|
Rv2043c More about Rv2043c on TBDB.org More about Rv2043c on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv2043c: Codons 30 to 34: 3 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Scorpio A AAC 1997 | del 118bp | 98-216 | - | Frameshift | 1992-1995 | - | PCR-SSCP | Whole gene | Z | >900ug/ml | Pzase testing by Wayne's method | 46/46 | 1/0 | - | - |
| Scorpio A AAC 1997 | ins T | 100 | 34 | Frameshift | 1992-1995 | - | PCR-SSCP | Whole gene | Z | >900ug/ml | Pzase testing by Wayne's method | 46/46 | 1/0 | - | - |
| Hirano K TLD 1997 | TAC/TCC | 101 | 34 | Tyr/Ser | 1997 | Thailand | Sequencing | Whole gene | ZHRSE | >800 | Proportion method | 33/168 | 2/0 | - |  |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
|
© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |