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Rv2043c More about Rv2043c on TBDB.org More about Rv2043c on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv2043c: Codons 165 to 169: 2 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Hou L Epi Infect 2000 | ins CG | 501 | - | Frameshift | 1996-1998 | China | PCR-SSCP | Whole gene | ZSHE | 900 | Proportion method, BACTEC 460 | 35/65 | 1/0 | - | - |
| Cheng SJ AAC 2000 | ACC/AAC | 503 | 168 | Thr/Asn | - | Canada | Sequencing | Whole gene | ZRO | 300 | Proportion method, BACTEC 460 | 59/59 | 1/0 | - | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |