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Rv2043c More about Rv2043c on TBDB.org More about Rv2043c on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv2043c: Codons 150 to 154: 3 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Lee KW J Korean Med Sci 2001 | del T | 452 | - | Frameshift | 2001 | South Korea | Sequencing | Whole gene | Z | - | PZase test with Wayne's method | 92/95 | 1/0 | - | - |
| Morlock GP AAC 2000 | ACC/AAC | 458 | 153 | Thr/Asn | 1999 | - | Sequencing | Whole gene | Z | 800 | Proportion method | 37/60 | 1/0 | - | - |
| Marttila HJ AAC 1999 | AGG/GGG | 460 | 154 | Arg/Gly | 1994-1997 | Russia | Sequencing | Whole gene | Z | - | BACTEC 460 | 36/44 | 1/0 | not tested | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |