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Rv2043c More about Rv2043c on TBDB.org More about Rv2043c on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv2043c: Codons 110 to 114: 3 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Hirano K TLD 1997 | ACG/CCG | 340 | 114 | Thr/Pro | 1997 | Yemen | Sequencing | Whole gene | ZHR | >800 | Middlebrook 7H11 agar w/ pH of 6.0 | 33/168 | 1/0 | - |  |
| Cheng SJ AAC 2000 | del C | 341 | - | Frameshift | - | South Korea | Sequencing | Whole gene | Z | >500 | Proportion method, BACTEC 460 | 59/59 | 1/0? | - | - |
| Lemaitre N AAC 1999 | ins 1355bp | 341 | - | Frameshift | 1989 | France | Sequencing | Whole gene | ZHRE | 1000 | - | 19/35 | 1/0 | - | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |