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Rv2428 More about Rv2428 on TBDB.org More about Rv2428 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail Display high confidence mutations only |
| Rv2428: high confidence mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Lee ASG AAC 1999 | G/A | -46 | -46 | - | 1994-1996 | Singapore | Sequencing | oxyRahpC intergenic region | H | 0.1ug/ml | BACTEC 460 | 160/192 | 1/0 | katG del/mut or inhA mutation |  |
| Silva MS JCM 2003 | C/T | -39 | -39 | - | 1996-1999 | Brazil | PCR-SSCP, Sequencing | oxyRahpC intergenic region | H,HR,HRS,HRP,HS,HRE,HRES,HRESP | - | Proportion method | 69/69 | 2/0 | none | |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |