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Rv2428 More about Rv2428 on TBDB.org More about Rv2428 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv2428: Codons 0 to 4: 3 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Gagneux S PLOS Path 2006 | T/C | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - |
| Lee ASG AAC 1999 | CCA/TCA | 4 | 2 | Pro/Ser | 1994-1996 | Singapore | Sequencing | Promoter region of ahpC | H | 0.1ug/ml | BACTEC 460 | 160/192 | 1/0 | katG del/mut or inhA mut | - |
| Kiepiela P Tuber Lung Dis 2000 | CTG/AAG | 7 | 3 | Leu/Lys | 1995 | South Africa | PCR-SSCP, Sequencing | N.S | H | >8ug/ml | BACTEC 460 | 79/96 | 1/0 | Pro2Pro ahpC, katG mut present but not specified | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |