|
|
           
|
|
|
|
|
|
|
|
 
|
|
Rv1908c More about Rv1908c on TBDB.org More about Rv1908c on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv1908c: Codons 700 to 719: 5 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Marttila HJ AAC 1996 | TCC/CCC | 2098 | 700 | Ser/Pro | 1989-1995 | Finland | Sequencing | Whole gene | H | 1 ug/ml | disk elution method | 54/56 | 1/0 | - | - |
| Secondary Publication: Ramaswamy S Musser JM Tubercle lung Dis 1998 | GTC/GCC | 2129 | 710 | Val/Ala | - | - | - | - | - | - | - | - | - | - | - |
| Secondary Publication: Hazbon MH AAC 2006 | GCC/CCC | 2137 | 713 | Ala/Pro | - | - | - | - | - | - | - | - | - | - | - |
| Secondary Publication: Hazbon MH AAC 2006 | CAG/CCG | 2150 | 717 | Gln/Pro | - | - | - | - | - | - | - | - | - | - | - |
| Rouse DA AAC 1995 | GCG/CCG | 2146 | 716 | Ala/Pro | 1995 | USA, South Korea | PCR-SSCP | Whole gene | HRP | 50ug/ml | Absolute concentration method | 26/26 | 1/0 | - | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
|
© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |