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Rv1908c More about Rv1908c on TBDB.org More about Rv1908c on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv1908c: Codons 620 to 639: 3 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Rouse DA AAC 1995 | GGC/AGC | 1888 | 629 | Gly/Ser | 1995 | - | PCR SSCP analysis | Whole gene | H | 1ug/ml | Absolute concentration method | 26/26 | 1/0 | - | - |
| Wei CJ AAC 2003 | CTC/TTC | 1900 | 634 | Leu/Phe | 2003 | - | - | - | - | - | - | - | - | - | - |
| Gagneux S PLOS Path 2006 | GCA/GAA | 1907 | 636 | Ala/Glu | - | - | - | - | - | - | - | - | - | - | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |