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Rv1908c More about Rv1908c on TBDB.org More about Rv1908c on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv1908c: Codons 200 to 219: 4 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Secondary Publication: Ramaswamy S Musser JM Tubercle lung Dis 1998 | AAG/TAG | 598 | 200 | Lys/STOP | - | - | - | - | - | - | - | - | - | - | - |
| Abe C JCM 2008 | - | - | 204 | Trp/Arg | Published in 2008 | Japan | Sequencing | Whole gene | H | - | MGIT 960 | 96/96 | 1/0 | - | - |
| Secondary Publication: Ramaswamy S Musser JM Tubercle lung Dis 1998 | ins | ? | 217 | Frameshift? | - | - | - | - | - | - | - | - | - | - | - |
| Chan RCY JAC 2007 | AAC/AAA | 654 | 218 | Asn/Lys | 1994-2004 | Hong Kong | PCR-SSCP, Sequencing | Whole gene | N.S. | - | Absolute concentration method | 250 | 241 | 1 | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |