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Rv1854c More about Rv1854c on TBDB.org More about Rv1854c on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv1854c: all mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Cardoso RF Mem Inst Oswaldo Cruz 2007 | CGT/TGT | 37 | 13 | Arg/Cys | 2006 | Brazil | Sequencing | Whole gene | H | >32ug/ml | Microplate alamar blue assay | 24/36 | 1/0 | S315T katG | - |
| Cardoso RF Mem Inst Oswaldo Cruz 2007 | GTG/GCG | 53 | 18 | Val/Ala | 2006 | Brazil | Sequencing | Whole gene | H | 32ug/ml | Microplate alamar blue assay | 24/36 | 1/0 | insA at nt17 katG | - |
| Lee ASG AAC 2001 | ACC/GCC | 328 | 110 | Thr/Ala | 1994-1996 | Singapore | Sequencing | Whole gene | H | - | BACTEC 460 | 84/106 | 1/0 | none | - |
| Secondary Publication: Hazbon MH AAC 2006 | CTG/CCG | 716 | 239 | Leu/Pro | - | - | - | - | - | - | - | - | - | - | - |
| Lee ASG AAC 2001 | CGC/CAC | 804 | 268 | Arg/His | 1994-1996 | Singapore | Sequencing | Whole gene | H | - | BACTEC 460 | 84/106 | 7/0 | - | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |