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Rv1484 More about Rv1484 on TBDB.org More about Rv1484 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv1484: Codons 95 to 99: 2 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Ristow M Lancet 1995 | ATT/CCT | 283-284 | 95 | Ile/Pro | 1995 | Germany, Nepal | Sequencing | inhA codon 94 | HEth | All 7 were resistant to I or Eth or both. | Proportion method | 38/47 | 7/0 | not mentioned | - |
| Secondary Publication: Ramaswamy S Musser JM Tubercle lung Dis 1998 | ATT/ACT | 284 | 95 | Ile/Thr | - | - | - | - | - | - | - | - | - | - | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |