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Rv1484 More about Rv1484 on TBDB.org More about Rv1484 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv1484: Codons 90 to 94: 2 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Lee H Int J Tuberc Lung Dis 2000 | TCG/GCG | 280 | 94 | Ser/Ala | 2000 | South Korea | Sequencing | nt174-382 | HR | 0.2ug/ml I, 20ug/ml R | - | 24/24 | 1/0 | - | - |
| Vilcheze C Nat Med 2006 | TCG/TTG | 281 | 94 | Ser/Leu | - | - | - | - | - | - | - | - | - | - | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |