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Rv1484 More about Rv1484 on TBDB.org More about Rv1484 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv1484: Codons 20 to 24: 2 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Morlock GP AAC 2003 | ATC/GTC | 61 | 21 | Ile/Val | 2003 | USA | Sequencing | 284 bp inhA promoter and nt 13-379 of inhA | HEth | 8ug/mlI, >200ug/ml Eth | Proportion metho | 41/42 | 2/0 | C(-15)T inhA regulator | - |
| Morlock GP AAC 2003 | ATC/ACC | 62 | 21 | Ile/Thr | 2003 | USA | Sequencing | 284 bp inhA promoter and nt 13-379 of inhA | HEth | >32ug/ml, 8ug/ml I, >200 ug/ml or 100ug/ml Eth | Proportion method | 41/42 | 3/0 | C(-15)T, G(-17)T inhA regulator, | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |