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Rv1483 More about Rv1483 on TBDB.org More about Rv1483 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail Display high confidence mutations only |
| Rv1483: high confidence mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Lee ASG AAC 1999 | C/T | -15 | -15 | - | 1994-1996 | Singapore | Sequencing | Promoter region of inhA | H | 0.1UG/ML | BACTEC 460 radimetric method | 160/192 | 43/0 | katG or ahpC-oxyR mut |  |
| Lee ASG AAC 1999 | T/A | -8 | -8 | - | 1994-1996 | Singapore | Sequencing | Promoter region of inhA | H | 0.1UG/ML | BACTEC 460 radimetric method | 160/192 | 1/0 | katG or ahpC-oxyR mut | |
| Baker LV AAC 2005 | T/C | -8 | -8 | - | 1998 | United Kingdom | Directed Oligonucleotide array, Sequencing | Promoter region of inhA | H,HS,HE,HSE,MDR | ratio>=4 | Resistance ratio method | 202/378 | 1/0 | none | |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |