Rv0005: gyrBRv0006: gyrA

Rv0006

More about Rv0006 on    TBDB.org

More about Rv0006 on    TubercuList

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Rv0006: Codons 60 to 79: 1 mutation (high confidence mutations are highlighted in yellow)
Primary reference Polymorphism Nucleotide position Codon position Amino acid Time period Origin Molecular detection method Gene coverage Resistance pattern MIC Susceptibility testing method R/Total isolates R/S isolates with mutation Additional mutations High confidence support
Shi R JCM 2006 GCC/TCC 220 74 Ala/Ser 2002-2003 China Sequencing 227bp QRDR gyrA OFX OFL 2-32 Absolute concentration method 87/109 10/0 gyrA: Asp94Gly

Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations.


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