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Rv0006 More about Rv0006 on TBDB.org More about Rv0006 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv0006: Codons 100 to 119: 2 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Kam KM Microb Drug Res 2006 | CCC/CAC | 305 | 102 | Pro/His | - | - | - | - | - | - | - | - | - | - |  |
| Sulochana S J Chemother 2007 | CTG/GTG | 325 | 109 | Leu/Val | Published 2007 | India | Sequencing | 320-bp gyrA QRDR, 360-bp gyrB QRDR | Moderately susceptible to OFX. | OFX: 2 | Absolute concentration method | 71/118 | 0/1 | - | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |