Rv1483: mabARv1484: inhARv3854c: ethA/etaA

Rv3854c

More about Rv3854c on    TBDB.org

More about Rv3854c on    TubercuList

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Display high confidence mutations only
Rv3854c: all mutations (high confidence mutations are highlighted in yellow)
Primary reference Polymorphism Nucleotide position Codon position Amino acid Time period Origin Molecular detection method Gene coverage Resistance pattern MIC Susceptibility testing method R/Total isolates R/S isolates with mutation Additional mutations High confidence support
DeBarber AE PNAS 2000 del 1bp 65 - Frameshift Published 2000 South Africa Sequencing Whole gene Eth N.S. Proportion method. 40132 1/0 None found in region analyzed. -
Morlock GP AAC 2003 del A 110 - Frameshift Published 2003 USA, Russia, Brazil Sequencing Whole gene HEth >200ug/ml Microplate almar blue assay 41/41 1/0 katG Ser315Thr -
DeBarber AE PNAS 2000 GGC/TGC 127 43 Gly/Cys Published 2000 South Africa Sequencing Whole gene HEth N.S. Proportion method. 40132 1/0 None found in region analyzed. -
Morlock GP AAC 2003 GGC/AGC 127 43 Gly/Ser Published 2003 USA, Russia, Brazil Sequencing Whole gene HEth >200ug/ml Microplate almar blue assay 41/41 1/0 katG Ser315Thr -
DeBarber AE PNAS 2000 CCC/CTC 152 51 Pro/Leu Published 2000 South Africa Sequencing Whole gene EthL N.S. Proportion method. 40132 1/0 None found in region analyzed. -
Morlock GP AAC 2003 GAC/GCC 167 55 Asp/Ala Published 2003 USA, Russia, Brazil Sequencing Whole gene HEth >200ug/ml Microplate almar blue assay 41/41 1/0 katG Gly279Asp, mabA -15 C/T -
DeBarber AE PNAS 2000 GAC/GCC 173 58 Asp/Ala Published 2000 South Africa Sequencing Whole gene Eth N.S. Proportion method. 40132 1/0 None found in region analyzed. -
DeBarber AE PNAS 2000 TAC/GAC 250 84 Tyr/Asp Published 2000 South Africa Sequencing Whole gene Eth N.S. Proportion method. 40132 1/0 None found in region analyzed. -
Morlock GP AAC 2003 ins A 338 - Frameshift Published 2003 USA, Russia, Brazil Sequencing Whole gene HEth 100ug/ml Microplate almar blue assay 41/41 1/0 katG Ser315Thr -
DeBarber AE PNAS 2000 ACG/AAG 557 186 Thr/Lys Published 2000 South Africa Sequencing Whole gene Eth N.S. Proportion method. 40132 1/0 None found in region analyzed. -
Morlock GP AAC 2003 GAG/AAG 667 223 Glu/Lys Published 2003 USA, Russia, Brazil Sequencing Whole gene HEth 50ug/ml Microplate almar blue assay 41/41 1/0 mabA -15 C/T -
Morlock GP AAC 2003 del T 703 - Frameshift Published 2003 USA, Russia, Brazil Sequencing Whole gene HEth >200ug/ml Microplate almar blue assay 41/41 1/0 katG Ser315Thr -
Morlock GP AAC 2003 CAG/TAG 736 246 Gln/STOP Published 2003 USA, Russia, Brazil Sequencing Whole gene HEth >200ug/ml Microplate almar blue assay 41/41 1/0 mabA -15 C/T -
Morlock GP AAC 2003 del G 768 - Frameshift Published 2003 USA, Russia, Brazil Sequencing Whole gene HEth >200ug/ml Microplate almar blue assay 41/41 1/0 katG Ser315Thr -
DeBarber AE PNAS 2000 ins 1 bp 811 - Frameshift Published 2000 South Africa Sequencing Whole gene HEth N.S. Proportion method. 40132 1/0 None found in region analyzed. -
DeBarber AE PNAS 2000 ACG/AAG 1025 342 Thr/Lys Published 2000 South Africa Sequencing Whole gene HEth N.S. Proportion method. 40132 3/0 None found in region analyzed. -
Morlock GP AAC 2003 ATC/AGC 1013 338 Ile/Ser Published 2003 USA, Russia, Brazil Sequencing Whole gene HEth 200ug/ml Microplate almar blue assay 41/41 1/0 katG Ser315Thr, mabA -15 C/T -
DeBarber AE PNAS 2000 GCC/CCC 1141 381 Ala/Pro Published 2000 South Africa Sequencing Whole gene HEth N.S. Proportion method. 40132 2/0 None found in region analyzed. -
Morlock GP AAC 2003 GGC/GAC 1154 385 Gly/Asp Published 2003 USA, Russia, Brazil Sequencing Whole gene HEth >200ug/ml Microplate almar blue assay 41/41 1/0 katG Ser315Thr, mabA -15 C/T -
Morlock GP AAC 2003 ACG/GCG 1174 392 Thr/Ala Published 2003 USA, Russia, Brazil Sequencing Whole gene HEth >200ug/ml Microplate almar blue assay 41/41 1/0 katG Ser315Thr -
Morlock GP AAC 2003 GGT/GAT 1238 413 Gly/Asp Published 2003 USA, Russia, Brazil Sequencing Whole gene HEth 50ug/ml Microplate almar blue assay 41/41 1/0 None found in region analyzed. -
Morlock GP AAC 2003 del C 1290 - Frameshift Published 2003 USA, Russia, Brazil Sequencing Whole gene HEth 50ug/ml Microplate almar blue assay 41/41 1/0 katG Ser315Thr -
Morlock GP AAC 2003 del GC 1322-1323 - Frameshift Published 2003 USA, Russia, Brazil Sequencing Whole gene HEth >200ug/ml Microplate almar blue assay 41/41 1/0 None found in region analyzed. -
Morlock GP AAC 2003 CGT/AGT 1387 463 Arg/Ser Published 2003 USA, Russia, Brazil Sequencing Whole gene HEth 50ug/ml Microplate almar blue assay 41/41 1/0 katG Trp341Ser, mabA -15 C/T -

Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations.

© 2010 Andreas Sandgren  |  Supported by the Swedish Research Council  |  Contact Database Curator