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Rv1484 More about Rv1484 on TBDB.org More about Rv1484 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv1484: all mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Lee H Int J Tuberc Lung Dis 2000 | TCG/GCG | 280 | 94 | Ser/Ala | Published 2000 | Korea | Sequencing | nt 174-384 | HEth, HREth | N.S. | Proportion method. | 40171 | 0/0 | Mutations in the regulatory region (mabA) were found. | - |
| Ristow M Lancet 1995 | AT/CC | 304-305 | 95 | Ile/Pro | Published 1995 | Germany, Nepal | Sequencing | region around inhA 94 | MDR | N.S. | Proportion method. | 32/47 | 7/0 | None found in the fragment analyzed. | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |