|
|
           
|
|
|
|
|
|
|
|
 
|
|
Rv1483 More about Rv1483 on TBDB.org More about Rv1483 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv1483: all mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Lee H Int J Tuberc Lung Dis 2000 | C/T | -15 | -15 | - | Published 2000 | South Korea | Sequencing | Whole | HEth, HREth | 40-80ug/ml | Proportion method. | 40171 | 40149 | No mutation in inhA94 found. | - |
| Morlock GP AAC 2003 | G/T | -17 | -17 | - | Published 2003 | USA, Russia, Brazil | Sequencing | Whole | EthH | 100ug/ml | Microplate almar blue assay | 41/41 | 1/0 | inhA Ile21Thr | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
|
© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |