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Rv3795 More about Rv3795 on TBDB.org More about Rv3795 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv3795: Codons 475 to 499: 2 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Ramaswamy SV AAC 2000 | CAG/CGG | 1490 | 497 | Gln/Arg | Published 2000 | USA, Russia | Sequencing | Whole gene | E | 30-50ug/ml | BACTEC 460, agar diffusion method | 75/108 | 3/0 | In one of the isolates: -12 C/T in embA, Ser501Trp in iniA. |  |
| Ramaswamy SV AAC 2000 | CAG/AAG | 1490 | 497 | Gln/Lys | Published 2000 | USA, Russia | Sequencing | Whole gene | E | 30-50ug/ml | BACTEC 460, agar diffusion method | 75/108 | 2/0 | "-12 C/T in embA at MIC=30ug/ml; -89 C/T in iniB at MIC>50ug/ml." | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |