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Rv3795 More about Rv3795 on TBDB.org More about Rv3795 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv3795: Codons 225 to 249: 4 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Jain A IndJMedRes 2008 | GCG/AGC | 673-674 | 225 | Ala/Ser | 2002-2004 | India | Sequencing | ERDR | EHRS | >20ug/ml | Proportion method, E-Test | 23/23 | 1/0 | None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1. | - |
| Jain A IndJMedRes 2008 | GTG/GGC | 680-681 | 227 | Val/Gly | 2002-2004 | India | Sequencing | ERDR | EHRS | >20ug/ml | Proportion method, E-Test | 23/23 | 1/0 | None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1. | - |
| Srivastava S CurrMicro 2006 | CTC/CCC | 716 | 239 | Leu/Pro | Published 2006 | India | Sequencing | ERDR | E, EHR, HR, EH | 256ug/ml | Proportion method, E-Test | 23/23 | 1/0 | None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1. | - |
| Srivastava S CurrMicro 2006 | GAC/CAC | 718 | 240 | Asp/His | Published 2006 | India | Sequencing | ERDR | E, EHR, HR, EH | 4ug/ml | Proportion method, E-Test | 23/23 | 1/0 | None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1. | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |