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Rv3793 More about Rv3793 on TBDB.org More about Rv3793 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv3793: Codons 975 to 999: 1 mutation (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Sreevatsan S AAC 1997 | GTG/CTG or GTG/TTG | 2941 | 981 | Val/Leu | Published 1997 | USA, Mexico, Europe, Yemen, the Philippines, Japan, India | PCR-SSCP, Sequencing | Whole gene | E | 15ug/ml | BACTEC 460, agar diffusion method | 16/19 | - | All three isolates also had a synonymous G/A substitution at nt 2898 of embA. | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |