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Rv3793 More about Rv3793 on TBDB.org More about Rv3793 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv3793: Codons 325 to 349: 3 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Srivastava S JMM 2009 | GGC/AGC | 973 | 325 | Gly/Ser | Published 2009 | India | Sequencing | Whole gene | EHR | 6ug/ml | Proportion method, E-Test | 44/44 | 1/0 | "embB M306I; embC T270I, Y296H, G308D" | - |
| Srivastava S JMM 2009 | TGG/CGT | 976-978 | 326 | Trp/Arg | Published 2009 | India | Sequencing | Whole gene | E | 3ug/ml | Proportion method, E-Test | 44/44 | 1/0 | "embB G358V, E368Q, S380D, P397T, G406D, G448V; embC I297L" | - |
| Srivastava S JMM 2009 | TAT/AAC | 979-981 | 327 | Tyr/Asn | Published 2009 | India | Sequencing | Whole gene | EHR | 96ug/ml | Proportion method, E-Test | 44/44 | 1/0 | "embB H312R, S317T, A356F, L359I, R367P; embC G288V, M310K" | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |