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Rv3793 More about Rv3793 on TBDB.org More about Rv3793 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv3793: Codons 225 to 249: 2 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Srivastava S JMM 2009 | GCG/ACC | 730-732 | 244 | Ala/Thr | Published 2009 | India | Sequencing | Whole gene | E | 6ug/ml | Proportion method, E-Test | 44/44 | 1/0 | "embB E368A, S380R, P397Q, R460C; embC G288W, V303G; embR L172R" | - |
| Srivastava S JMM 2009 | GCC/CCG | 739-741 | 247 | Ala/Pro | Published 2009 | India | Sequencing | Whole gene | EH | 8ug/ml | Proportion method, E-Test | 44/44 | 1/0 | "embB A356F, A357V, L359I, E378A, A379D, Y384N, A388G, N399D; embC T270I, I297T" | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |