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Rv1267c More about Rv1267c on TBDB.org More about Rv1267c on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv1267c: Codons 350 to 359: 3 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Srivastava S JMM 2009 | GTG/GGC | 1049-1050 | 350 | Val/Gly | Published 2009 | India | Sequencing | Whole gene | EHR | 2ug/ml | Proportion method, E-Test | 44/44 | 1/0 | "embB A357S, A379T; embC V287F, Y309N; embR L320V, S326N, H351Q, R356G, I369T" | - |
| Srivastava S JMM 2009 | CAT/CAG | 1053 | 351 | His/Glu | Published 2009 | India | Sequencing | Whole gene | EHR | 2ug/ml | Proportion method, E-Test | 44/44 | 1/0 | "embB A357S, A379T; embC V287F, Y309N; embR L320V, S326N, V350G, R356G, I369T" | - |
| Srivastava S JMM 2009 | CGT/GGC | 1066-1068 | 356 | Arg/Gly | Published 2009 | India | Sequencing | Whole gene | EHR | 2ug/ml | Proportion method, E-Test | 44/44 | 1/0 | "embB A357S, A379T; embC V287F, Y309N; embR L320V, S326N, V350G, H351Q, I369T" | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |