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Rv1267c More about Rv1267c on TBDB.org More about Rv1267c on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv1267c: Codons 170 to 179: 2 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Srivastava S JMM 2009 | CTG/CGT | 515-516 | 172 | Leu/Arg | Published 2009 | India | Sequencing | Whole gene | EHR | 4ug/ml | Proportion method, E-Test | 44/44 | 1/0 | "embB E368A, S380R, P397Q, R460C; embC A244T, G288W, V303G" | - |
| Srivastava S JMM 2009 | GCG/GTG | 527 | 176 | Ala/Val | Published 2009 | India | Sequencing | Whole gene | EHR | 6ug/ml | Proportion method, E-Test | 44/44 | 1/0 | "embB V360M, A431T; embC G272S, H285Y, M300R, A307T; embR I369T" | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |