Rv0340Rv0341: iniBRv0342: iniARv0343: iniCRv1267c: embRRv3124Rv3125cRv3126Rv3264c: rmlA2Rv3266c: rmlDRv3793: embCRv3794: embARv3795: embB

Rv0342

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Rv0342: Codons 300 to 319: 1 mutation (high confidence mutations are highlighted in yellow)
Primary reference Polymorphism Nucleotide position Codon position Amino acid Time period Origin Molecular detection method Gene coverage Resistance pattern MIC Susceptibility testing method R/Total isolates R/S isolates with mutation Additional mutations High confidence support
Ramaswamy SV AAC 2000 - - 308 Gly/Arg Published 2000 USA, Russia Sequencing Whole gene E >50ug/ml BACTEC 460, agar diffusion method 75/108 1/0 Gly745Asp in embB -

Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations.


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