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Rv0340 More about Rv0340 on TBDB.org More about Rv0340 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv0340: Codons 170 to 174: 1 mutation (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Ramaswamy SV AAC 2000 | - | - | 173 | Thr/Met | Published 2000 | USA, Russia | Sequencing | Whole gene | E | N.S. | BACTEC 460, agar diffusion method | 75/108 | 1/0 | "All three resistant isolates also had resistance-associated mutations in embC (n=1) or embB (n=3); see Note." | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |