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Rv1694 More about Rv1694 on TBDB.org More about Rv1694 on TubercuList |
Display all mutations or select a bar from the histogram above to examine in greater detail |
| Rv1694: Codons 235 to 239: 2 mutations (high confidence mutations are highlighted in yellow) | |||||||||||||||
| Primary reference | Polymorphism | Nucleotide position | Codon position | Amino acid | Time period | Origin | Molecular detection method | Gene coverage | Resistance pattern | MIC | Susceptibility testing method | R/Total isolates | R/S isolates with mutation | Additional mutations | High confidence support |
| Maus CE AAC 2005 Feb | AAT/AAG | 708 | 236 | Asn/Lys | Published 2005 | USA | Sequencing | Whole gene | HSCapVio | K <5ug/ml Cap 80ug/ml | Proportion method | 16/18 | 0/1 | None found in region analyzed. | - |
| Maus CE AAC 2005 | G/A | 712 | 238 | Glu/Lys | Published 2005 | USA | Sequencing | Whole gene | Cap | N.S. | Proportion method | 30/30 | 1/0 | None identified specifically. | - |
Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations. |
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© 2010 Andreas Sandgren | Supported by the Swedish Research Council | Contact Database Curator |